研究领域
主要从事分子诊断与生化分析领域的研究,研究方向包括新型核酸扩增原理设计、CRISPR/Cas传感系统开发、简便快速可视化传感体系构建、DNA水凝胶应用、高灵敏度高特异性生物标志物检测方法、电化学生物标志物传感策略以及单细胞分析等。
科研项目
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IDSP-IA: Immunotriggered Double Stem-Loop Probe-Mediated Isothermal Amplification for Attomolar Protein Quantification.[J].Analytical Chemistry,2025,97(41):22692-22699.
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CRISPR/Cas12a-responsive and capillarity-powered DNA hydrogel distance sensor for point-of-care DNA detection.[J].Biosensors and Bioelectronics,2024,264:116657.
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CRISPR/Cas13a-responsive and RNA-bridged DNA hydrogel capillary sensor for point-of-care detection of RNA.[J].Analytical Chemistry,2024,96(29):12022−12029.
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Dual CRISPR/Cas13a cascade strand displacement-triggered transcription for point-of-care detection of Plasmodium in asymptomatic malaria.[J].Analytical Chemistry,2024,96(19):7524-752.
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Single-microbead space-confined digital quantification strategy (SMSDQ) for counting microRNAs at the single-molecule level.[J].Biosensors and Bioelectronics,2023,238:115578.
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