研究领域

•  生化分析与分子诊断，从事核酸、蛋白质生物标志物的高灵敏度分析与疾病诊断、微纳界面的生物传感分析、单细胞分析及高通量核酸测序分析研究。

科研项目

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论文成果 More>>

• CRISPR/Cas12a-Assisted Ligation-Initiated Loop-Mediated Isothermal Amplification (CAL-LAMP) for Highly Specific Detection of microRNAs.
• Ultrasensitive homogeneous detection of microRNAs in a single cell with specifically designed exponential amplification.
• Ultrasensitive detection of tumor-specific exosomal proteins by a Single Microbead-based Aptasensor coupled with Terminal deoxynucleotidyl transferase-initiated DNA amplification (SMAT).
• Ultrasensitive multiplexed detection of miRNA targets of interest based on encoding probe extension in improved cDNA library.
• Single microbead-based fluorescent aptasensor (SMFA) for direct isolation and in situ quantification of exosomes from plasma.

专利软著

• Smart Equipment-Assisted Quantitative Analysis for Nucleic Acids and Use of the Same
• 一种基于智能设备辅助的核酸定量分析方法及其应用
• T3 DNA连接酶和T4 RNA连接酶2在检测N6甲基腺嘌呤中的应用
• 一种基于连接反应构建双茎环结构DNA模板检测核酸的方法
• 一种茎环结构组合探针及其应用

著作成果

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